Advanced Practice Registered Nurse (APRN)

Nursing Career Guide

Advanced Practice Registered Nurse providing primary care as part of her APRN job duties.
Advanced Practice Registered Nurse (APRN) include nurse practitioners, clinical nurse specialists, nurse anesthetists, and nurse midwives, each with their specialized scope of nursing practice.

What Is an Advanced Practice Registered Nurse?


An Advanced Practice Registered Nurse (APRN) is a highly trained nurse who holds at least a master's degree in nursing and provides advanced clinical care. APRN have greater autonomy than traditional Registered Nurses and can diagnose conditions, prescribe medications, and develop treatment plans.

APRN include four main types of roles: Nurse Practitioners (NP), Clinical Nurse Specialists (CNS), Certified Nurse Midwives (CNM), and Certified Registered Nurse Anesthetists (CRNA). Each specialty serves different patient populations and focuses on various aspects of care, from anesthesia and labor support to primary care and acute clinical consultation.

This career requires advanced clinical expertise, strong decision-making skills, and the ability to work independently in both collaborative and autonomous practice settings.

How To Become an Advanced Practice Registered Nurse


Becoming an Advanced Practice Registered Nurse requires a combination of advanced nursing education, certification, and specialized clinical experience. Follow these steps to enter this challenging and rewarding healthcare career:

  1. Earn a BSN. Complete a Bachelor of Science in Nursing (BSN) degree as the foundation for graduate-level nursing education.
  2. Pass the NCLEX-RN. Obtain licensure as a Registered Nurse (RN) by passing the National Council Licensure Examination.
  3. Gain Clinical Experience. Work in a clinical nursing role for 1-2 years to develop foundational experience in patient care.
  4. Earn a Graduate Nursing Degree. Enroll in a Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) program specializing in one of the four APRN roles.
  5. Pass National Certification. Take a certification exam specific to your APRN role and population focus area, such as family practice or acute care.
  6. Apply for APRN Licensure. Obtain state licensure as an APRN according to your state board of nursing regulations.

How long does it take to become an APRN? It typically takes 6 to 8 years to become an Advanced Practice Registered Nurse. This includes undergraduate and graduate education, clinical experience, and national certification. Some APRN pursue doctoral-level training for leadership, research, or advanced clinical roles.

Advanced Practice Registered Nurse (APRN) administers anesthesia as part of her job duties.
A Nurse Anesthetist (CRNA) is a type of Advanced Practice Registered Nurse (APRN) who specializes in administering anesthesia and related care during surgical, diagnostic, and therapeutic procedures.

How Much Does an Advanced Practice Registered Nurse Make?


APRN earn significantly higher salaries than standard RN due to their advanced education and expanded scope of practice. On average, an Advanced Practice Registered Nurse can expect to earn between $100,000 and $160,000 annually, depending on their specialty.

Average annual salary for an Advanced Practice Registered Nurse:

  • Entry-level: $100,000 - $120,000 per year.
  • Mid-career: $120,000 - $140,000 per year.
  • Experienced: $140,000 - $160,000 per year.

The U.S. Department of Labor provides separate salary estimates for APRN roles. For example, Nurse Practitioners earn an average of $124,680 per year, while Nurse Anesthetists earn around $203,090. Certified Nurse Midwives average $120,880 annually. These salaries reflect a 40-hour workweek but may increase for those in private practice, rural health, or nursing leadership positions.

What Does an Advanced Practice Registered Nurse Do?


APRN provide advanced-level care and frequently serve as primary care providers or specialists in hospitals, clinics, and private practices. They diagnose, treat, and manage both acute and chronic conditions across diverse populations. The most common job duties of an Advanced Practice Registered Nurse include:

  • Performing Physical Exams. Assess patients using advanced diagnostic techniques and clinical judgment.
  • Diagnosing and Treating Illnesses. Manage common acute and chronic conditions, order diagnostic tests, and initiate treatment plans.
  • Prescribing Medications. Evaluate the need for prescriptions and provide medication management within the APRN scope of practice.
  • Developing Care Plans. Create comprehensive care plans tailored to individual patient needs and health goals.
  • Providing Specialized Services. Depending on the role, APRN may assist in labor and delivery, administer anesthesia, or consult on complex clinical cases.
  • Educating Patients and Families. Teach disease prevention, wellness, and self-care strategies for long-term health.
  • Collaborating with Physicians. Work alongside physicians, surgeons, and interdisciplinary teams, or practice independently in some states.
  • Advanced Duties. APRN may engage in research, mentor nurses, or contribute to healthcare policy and quality improvement initiatives.

APRN are found in nearly every healthcare setting, from rural clinics to major hospitals. Their advanced clinical skills and holistic approach make them essential providers in improving patient access and outcomes. In states with full practice authority, many APRN open and operate their own independent clinics, giving them flexibility in how and where they deliver care.

Advanced Practice Registered Nurse (APRN) working in a labor and delivery as part of her job duties..
A Certified Nurse Midwife (CNM) is an Advanced Practice Registered Nurse (APRN) who specializes in providing care to women during pregnancy, childbirth, and the postpartum period, as well as gynecological care.

What Skills Does an Advanced Practice Registered Nurse Need?


APRN need advanced clinical judgment, leadership skills, and the ability to handle complex patient care decisions. They must balance patient care with collaboration, documentation, and continuous learning. Here are some of the skills an Advanced Practice Registered Nurse needs to succeed:

  • Advanced Assessment and Diagnosis. Conduct thorough patient evaluations and interpret diagnostic data accurately.
  • Clinical Decision-Making. Make evidence-based decisions in high-stakes, time-sensitive clinical situations.
  • Prescriptive Authority. Safely prescribe and manage medications in accordance with state laws and protocols.
  • Communication. Explain complex medical concepts clearly to patients, families, and care teams.
  • Autonomy. Operate independently within your scope of practice while adhering to clinical standards.
  • Leadership. Guide nursing teams, participate in policy discussions, and lead quality improvement efforts.
  • Research and Evidence-Based Practice. Integrate the latest research into clinical decision-making and patient education.
  • Specialty Expertise. Develop deep knowledge in your specific APRN role, such as pediatrics, women's health, anesthesia, or geriatric nursing.

One of the biggest challenges of being an APRN is balancing clinical responsibilities with regulatory requirements and evolving scopes of practice. However, the role is exceptionally rewarding, offering clinical autonomy, higher pay, and the ability to make a profound impact on patient care and health systems.

Where Does an Advanced Practice Registered Nurse Work?


Advanced Practice Registered Nurses (APRN) work in a variety of clinical and non-clinical settings, depending on their certification type and area of specialization. The most common workplaces for an Advanced Practice Registered Nurse include:

  • Hospitals and surgical centers. Provide advanced care in departments such as emergency, cardiology, oncology, and surgery, often working alongside physicians or independently under state scope of practice laws.
  • Private practices. Diagnose and treat patients in primary care, women's health, or mental health settings, sometimes operating independently or as part of a collaborative care team.
  • Community health centers. Offer accessible care to underserved populations, focusing on prevention, chronic disease management, and patient education.
  • Universities and research institutions. Teach in nursing programs or contribute to clinical research aimed at improving patient outcomes and healthcare systems.
  • Rural clinics and specialty outreach programs. Deliver comprehensive care in remote locations or medically underserved areas, where APRN may serve as the lead provider due to physician shortages.

Advanced Practice Registered Nurses enjoy flexibility in their work setting and scope of responsibilities. Some choose to split their time between clinical practice and teaching, while others manage their own clinics, engage in policymaking, conduct research, or take on leadership roles within healthcare organizations.

Last updated: May 22, 2025

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